Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative care: A randomized clinical trial

This study found that for patients receiving palliative care, patients who had individualised management of precipitating factors for delirium and supportive strategies had better outcomes than patients who received risperidone or haloperidol.

Reference: Agar MR, Lawlor PG, Quinn S, Draper B, Caplan GA, Rowett D et al. Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium among patients in palliative care: A randomized clinical trial. JAMA Internal Medicine 2017; 177: 34-42.